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The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive Techniques

NCT01773512 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2013-01-23

No results posted yet for this study

Summary

* The prediction of extent and risk profile of coronary atherosclerosis based on clinical evaluation and non-invasive techniques.
* Detailed analysis of plaque volume, plaque composition, risk plaque features and shear stress (WSS) changes during lipid lowering therapy (rosuvastatin 40mg) from 3D vessel reconstruction.
* Prediction of changes in coronary arteries based on changes in non-invasive examinations.
* Examination of WSS influence on atherosclerosis development and changes of WSS during lipid lowering therapy.

Conditions

Interventions

DRUG

Rosuvastatin

All patients will be using rosuvastatin 40 mg

Sponsors & Collaborators

  • Ministry of Health, Czech Republic

    collaborator OTHER_GOV

  • Czech Ministry of Education

    collaborator OTHER_GOV

  • University of Iowa

    collaborator OTHER

  • Loyola University Chicago

    collaborator OTHER

  • General University Hospital, Prague

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2014-12-31
Completion
2015-06-30

Countries

  • United States
  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01773512 on ClinicalTrials.gov