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Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression

NCT06363981 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2024-10-15

No results posted yet for this study

Summary

Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat. rTMS is a relatively novel treatment option, whose therapeutic potential is still investigated and optimized. The aim of this study is to assess the effect of rTMS applied over two stimulation sites on cognitive impairment, anhedonia and sleep disorders in depression.

Conditions

Interventions

DEVICE

Active rTMS over the left DLPFC and over the left DMPFC

Active rTMS over the left DLPFC and over the left DMPFC to induce the long term potentiation of stimulated areas.

DEVICE

Active rTMS over the left DLPFC

Active rTMS over the left DLPFC to induce the long term potentiation of stimulated area.

DEVICE

Sham rTMS

Sham rTMS over the left DLPFC or over the left DLPFC and over the left DMPFC for placebo.

Sponsors & Collaborators

  • Andrzej Frycz Modrzewski Krakow University

    collaborator OTHER

  • Jakub Antczak

    lead OTHER

Principal Investigators

  • Wojciech Korzeniowski, MD · The Education of Research and Development Center, Babinski Clinical Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-20
Primary Completion
2026-12-31
Completion
2027-04-30

Countries

  • Poland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06363981 on ClinicalTrials.gov