Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
NCT00916851 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2021-09-02
Summary
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common early-onset neuropsychiatric disorders. Little is known about the discriminative validity between these two disorders. As brain imaging studies have been recognized as an important biological tool to validate disease involving the brain, no studies have employed this approach to distinguish the brain functioning between ASD and ADHD. Moreover, there is lack of comprehensive data of environmental, behavioral, neurocognitive, neuroimaging, and genetic data for healthy children. Hence, we propose this program project involving expertise researchers in the fields of child psychiatry and psychology, psychiatric genetics, and brain imaging studies to elucidate the neuropathophysiology and genes \& environment interactions of ASD and ADHD as comparing to healthy controls by integrating data from environments, behavioral phenotypes, endophenotypes, and genotypes in one study.
Conditions
- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Susan Shur-Fen Gau, MD, PhD · National Taiwan University Hospital & College of Medicine
Eligibility
- Min Age
- 8 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-08-01
- Primary Completion
- 2013-07-31
- Completion
- 2013-07-31
Countries
- Taiwan
Study Locations
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