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Microbiota in Gastric Cancer by Gastric Mucosal Brushing

NCT06325891 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2024-05-07

No results posted yet for this study

Summary

Many studies have shown a significant change of diversity and composition in gut microbiota across the gastric carcinogenesis process, particularly in patients with gastric cancer. However, there has been no analysis of gastric microbiota using the mucosal brushing technique, despite its favoring benefit in microbiota study. Therefore, this study aims to evaluate microbiota profile in patients with gastric cancer, compared to those without gastric cancer by using mucosal brush sampling. This will improve current knowledge of the potential role of the microbiome in patient gastric cancer as a future biomarker marker using brushing sampling.

Conditions

Interventions

DIAGNOSTIC_TEST

Gastric mucosal brushing

Gastric mucosal brushing will be performed at body of stomach in control group and non-tumorous area of body in gastric cancer group. If gastric body area could not feasible (eg. tumor involvement), then gastric antrum and more proximal part of body will be sampling.

DIAGNOSTIC_TEST

Gastric mucosal biopsy

Gastric mucosal biopsy will be performed at the area within 2 cm. from brushing site.

Sponsors & Collaborators

  • King Chulalongkorn Memorial Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-01
Primary Completion
2025-03-31
Completion
2025-05-31

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06325891 on ClinicalTrials.gov