Study of Gut Microbiome and Colorectal Tumors
NCT03297996 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 540
Last updated 2017-09-29
Summary
Gut microbiota were assessed in 540 colonoscopy-screened adults by 16S rRNA gene sequencing of stool samples. Investigators compared gut microbiota diversity, overall composition, and normalized taxon abundance among these groups.
Conditions
- Serrated Polyp
- Hyperplastic Polyp
- Sessile Serrated Adenoma
- Colorectal Cancer
Interventions
- DIAGNOSTIC_TEST
-
Mobio PowerSoil DNA Isolation Kit
16S rRNA amplicons covering variable regions V3 to V4 were generated using primers (347F-5'GGAGGCAGCAGTRRGGAAT'-3' and 803R 5'-CTACCRGGGTATCTAATCC-3') incorporating Roche 454 FLX Titanium adapters (Branford, CT) and a sample barcode sequence
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Jiyoung Ahn, MD · NYU Langone Health
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-11-23
- Primary Completion
- 2015-04-25
- Completion
- 2015-04-25
Countries
- United States
Study Locations
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