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Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad Breath

NCT06219226 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-08-05

No results posted yet for this study

Summary

The ODOR trial will be a single-centric, double-blinded, parallel-group, double-armed pilot randomized controlled trial with a non-inferiority design. The efficacy of hyperpure chlorine dioxide will be compared to chlorhexidine mouthwash. The short-term effect of the mouthwashes will be investigated in a 3-hour-long period. The primary endpoint will be the changes in the organoleptic testing scores.

Conditions

  • Halitosis

Interventions

PROCEDURE

Chlorine dioxide mouthwash

This one rinsing will last 2x15 seconds(2x12,5ml).

PROCEDURE

Chlorhexidine mouthwash

This one rinsing will last 2x15 seconds(2x12,5ml).

Sponsors & Collaborators

  • Semmelweis University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-18
Primary Completion
2025-12-18
Completion
2025-12-18

Countries

  • Hungary

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06219226 on ClinicalTrials.gov