Clinical and Microbiological Effects of a Mouthwash Containing Chlorine Dioxide
NCT00748943 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2008-09-12
Summary
Previous research has shown the oxidizing properties and microbiological efficacies of chlorine dioxide (ClO2). However, no clinical studies have investigated its microbiological efficacies on periodontal and malodorous bacteria. The aim of this study was to assess the inhibitory effects of a mouthwash containing ClO2 on morning oral malodor and on salivary periodontal and malodorous bacteria using for 7 days.
Conditions
- Halitosis
Interventions
- OTHER
-
Chlorine Dioxide
Experimental mouthwash (ClO2 Fresh®) contained 0.16% sodium chlorite (NaClO2)
Sponsors & Collaborators
-
Tokyo Medical and Dental University
lead OTHER
Principal Investigators
-
Kayoko Shinada, DDS,phD · Dept. of Oral health promotion, Tokyo medical and dental university
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 19 Years
- Max Age
- 38 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-03-31
- Primary Completion
- 2007-05-31
- Completion
- 2007-06-30
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