GIP/GLP-1 Co-Activity in Subjects With Overweight and Type 2 Diabetes: Lowering of Food Intake
NCT03526289 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2018-12-05
Summary
The primary aim of the study is to evaluate how GIP receptor activation influence food intake and mechanisms regulating food intake in obese individuals with type 2 diabetes that are in steady treatment with metformin and a GLP-1 receptor agonist.
Conditions
- Type 2 Diabetes Mellitus
- Overweight and Obesity
Interventions
- BIOLOGICAL
-
GIP1-42 infusion
5-hour GIP1-42 infusion (time point 0-300 minutes)
- OTHER
-
Saline
5-hour infusion of saline (placebo) (time point 0-300 minutes)
Sponsors & Collaborators
- collaborator INDUSTRY
-
University Hospital, Gentofte, Copenhagen
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-08
- Primary Completion
- 2018-10-24
- Completion
- 2018-10-24
Countries
- Denmark
Study Locations
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