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Pediatric Induction Therapy in Kidney Transplantation

NCT06087003 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 958

Last updated 2023-10-17

No results posted yet for this study

Summary

The goal of this observational study is to compare the efficacy of two most commonly used induction therapy for the prevention of acute rejection (AR) after renal transplantation in children. The main question it aims to answer is:

Is basiliximab (anti-CD25 monoclonal antibody) induction therapy effective and safe in preventing AR after kidney transplantation in children compared with anti-thymoglobulin polyclonal antibodies induction therapy?

The transplant and follow-up data of participants will be retrospectively collected.

Researchers will compare the rate of AR to see if basiliximab (anti-CD25 monoclonal antibody) induction therapy is a better option for certain pediatric kidney transplant recipients.

Conditions

  • Kidney Transplant Rejection
  • Pediatric Kidney Disease

Interventions

DRUG

Basiliximab Injection

As an induction treatment for kidney transplantation

DRUG

rabbit ATG

As an induction treatment for kidney transplantation

Sponsors & Collaborators

  • Zhejiang University

    collaborator OTHER

  • First Affiliated Hospital, Sun Yat-Sen University

    collaborator OTHER

  • The First Affiliated Hospital of Zhengzhou University

    collaborator OTHER

  • Changhai Hospital

    collaborator OTHER

  • Gang Chen

    lead OTHER

Principal Investigators

  • Gang Chen, PhD · Tongji Hospital

Eligibility

Min Age
1 Month
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-03
Primary Completion
2022-07-27
Completion
2023-09-30
FDA Drug
Yes

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06087003 on ClinicalTrials.gov