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Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

NCT00018785 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2009-01-21

No results posted yet for this study

Summary

Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of modulating the immune response in kidney transplantation, thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.

Conditions

Interventions

PROCEDURE

donor bone marrow infusion

Sponsors & Collaborators

Principal Investigators

  • Camillo Ricordi, M.D.

  • Andreas Tzakis, M.D.

  • Violet Esquenazi, Ph.D.

  • Keith Zucker, Ph.D.

Study Design

Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1998-10-31
Completion
2003-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00018785 on ClinicalTrials.gov