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B Cell Lymphocyte in Humoral Rejection and Alloimmunisation

NCT03016455 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2017-05-04

No results posted yet for this study

Summary

This study aims to better characterise B cell phenotype and functional abnormalities in kidney transplant patients producing donor specific antibody (DSA) and in those with chronic antibody mediated rejection (cAMR) and to search for a predictive tool (biomarker). The functional analysis will help to better understand B cell-dependant mechanisms implied in T cell proliferation and better target future treatments.

Conditions

  • Renal Transplant

Interventions

OTHER

Presence of DSA w/ cAMR

OTHER

Presence of DSA w/o cAMR

OTHER

No DSA No cAMR

Sponsors & Collaborators

  • University Hospital, Brest

    lead OTHER

Principal Investigators

  • Yannick LE MEUR, MD PhD · University Hospital, Brest

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03016455 on ClinicalTrials.gov