Cardiac Structure and Function in Patients with Cystic Fibrosis

Summary

In a prospective observational cohort study (n = 100), the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and cystic fibrosis genotype and severity and determine whether these are prognostic markers of heart disease in patients suffering from cystic fibrosis (CF).

Conditions

• Cystic Fibrosis
• Cystic Fibrosis-related Diabetes
• Cystic Fibrosis, Pulmonary
• Cystic Fibrosis of Pancreas
• Cystic Fibrosis Gastrointestinal Disease
• Cystic Fibrosis Modifier 1
• Left Ventricular Dysfunction
• Heart Failure
• Heart Failure, Systolic
• Heart Failure, Diastolic
• Myocardial Infarction
• Stroke
• Heart Diseases

Sponsors & Collaborators

• Copenhagen University Hospital, Denmark

  collaborator OTHER

• Herlev and Gentofte Hospital

  lead OTHER

Principal Investigators

• Tor Biering-Sørensen, Professor MD PhD MPH · Department of Cardiology, Department of Biomedical Sciences, Herlev and Gentofte University Hospital, University of Copenhagen

• Susanne D Poulsen, MD DMSc · Viro-immunology Research Unit, Department of Infectious Diseases 8632, Copenhagen University Hospital Rigshospitalet, University of Copenhagen

• Daniel Faurholt-Jepsen, MD PhD · CF Centre Copenhagen University Hospital Rigshospitalet

• Terese L Katzenstein, MD PhD DMSc · CF Centre Copenhagen University Hospital Rigshospitalet

• Tacjana Pressler, MD · CF Centre Copenhagen University Hospital Rigshospitalet

• Rebekka F Thudium, MD PhD · CF Centre Copenhagen University Hospital Rigshospitalet

• Lisa S Duus, MD · Department of Cardiology, Department of Biomedical Sciences, Herlev and Gentofte University Hospital, University of Copenhagen

• Maria Dons, MD · Department of Cardiology, Department of Biomedical Sciences, Herlev and Gentofte University Hospital, University of Copenhagen

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-01-01

Primary Completion

2023-03-01

Completion

2032-03-01

Countries

• Denmark

Study Locations