Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer
NCT06080061 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2026-04-07
Summary
The purpose of this study is to examine the use of hypofractionated accelerated radiation therapy (HART) to treat locally advanced lung cancer. Depending on the location and size of the tumor.
Conditions
Interventions
- RADIATION
-
Hypofractionated accelerated radiation therapy
Hypofractionated accelerated radiation therapy
Sponsors & Collaborators
-
LUNGevity Foundation
collaborator OTHER - lead OTHER
Principal Investigators
-
Joseph A Jaoude, MD · Stanford University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-10-25
- Primary Completion
- 2026-11-30
- Completion
- 2026-12-31
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Can Not Be Surgically Removed
NCT00003235 ·Status: COMPLETED ·Phase: PHASE3
-
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
NCT05624996 ·Status: RECRUITING ·Phase: PHASE3
-
Paclitaxel and Irinotecan in Treating Patients With Advanced Non-small Cell Lung Cancer
NCT00004924 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative
NCT04929041 ·Status: SUSPENDED ·Phase: PHASE2/PHASE3
-
Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of HL301 on Radiation Pneumonitis in Non-small Cell Lung Cancer Patients
NCT04632342 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy Combined With Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
NCT00059761 ·Status: COMPLETED ·Phase: PHASE1
-
Gemcitabine, Carboplatin or Paclitaxel Plus Radiation Therapy in Treating Patients With Stage IIIA or IIIB Non-Small Cell Lung Cancer
NCT00016315 ·Status: COMPLETED ·Phase: PHASE1
-
Locally Advanced NSCLC Hyperfractionated RT
NCT03128008 ·Status: COMPLETED ·Phase: PHASE2
-
Accelerated Radio-Immunotherapy for Lung Cancer
NCT04577638 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
NCT00022308 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)
NCT07154706 ·Status: RECRUITING ·Phase: PHASE3
-
MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy
NCT01294306 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotherapy With Non-Ablative Radiation in Previously Untreated Patients With Stage IV NSCLC
NCT05691829 ·Status: TERMINATED ·Phase: PHASE2
-
A Pilot Study of Response-Driven Adaptive Radiation Therapy for Patients With Locally Advanced Non-Small Cell Lung Cancer
NCT02492867 ·Status: COMPLETED ·Phase: NA
-
Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery
NCT00553462 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer
NCT02521051 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00280150 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Neoadjuvant LDRT Combined With Durvalumab in Potentially Resectable Stage III NSCLC
NCT05157542 ·Status: UNKNOWN ·Phase: PHASE1
-
Hypo-Hyperfractionated Chest Radiation for Non Small Cell Lung Cancer With Taxotere/Xeloda Combination Chemotherapy
NCT00256841 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
NCT00979212 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab, Paclitaxel, Carboplatin, and Radiation Therapy to the Chest in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer
NCT00369551 ·Status: TERMINATED ·Phase: PHASE1
-
Combination Chemotherapy, Radiation Therapy, and Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00040794 ·Status: COMPLETED ·Phase: PHASE2
-
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
NCT07227298 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Paclitaxel Plus Radiation Therapy in Treating Patients With Untreated Stage III Non-small Cell Lung Cancer
NCT00002519 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin, Paclitaxel, Bevacizumab and Vorinostat for Patients With Advanced Non-Small Cell Lung Cancer
NCT00702572 ·Status: TERMINATED ·Phase: PHASE1