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Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data

NCT06028620 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2023-12-01

No results posted yet for this study

Summary

The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children. The main question it aims to answer are: which are the clinical characteristics of maltreated children before and after a psychological intervention? what changes in brain emotional processing after a psychological intervention? and what is the effect of serotonin transporter variants after a psychological therapy? Participants were assessed before and after intervention with:

* clinical measures of anxiety, depression post-traumatic stress and callous-unemotional traits
* functional neuroimaging techniques to measure brain activity.
* A sample of buccal epithelial cells to obtain information on serotonin transporter.

Researchers will compare maltreated children with a group on non-maltreated children to see if there are differences on psychological characteristics and on brain activity before treatment.

Conditions

  • Psychopathic Personality Trait

Interventions

BEHAVIORAL

Trauma Focused-Cognitive Behavior Therapy

TF-CBT consisted of 8 units in which different issues realted to trauma are reviewed. Units are: psychoeducation and parenting skills, relaxation techniques, affective expression and regulation, cognitive coping and processing, trauma narrative and processing, in vivo exposure, co-joint sessions and enhancing safety and future growth.

Sponsors & Collaborators

  • Universidad Nacional Autonoma de Mexico

    lead OTHER

Principal Investigators

  • Feggy Ostrosky, Ph.D. · Facultad de Psicología UNAM

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
7 Years
Max Age
12 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-01
Primary Completion
2021-11-01
Completion
2022-06-01

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06028620 on ClinicalTrials.gov