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Changes in Inhibition and Valuation After Eating

NCT05995496 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-02-17

No results posted yet for this study

Summary

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for treatment. This project aims to understand how predictions and value-based decisions about control may be abnormally influenced by eating in individuals with BN, thereby maintaining cycles of binge eating, purging, and restriction.

Conditions

  • Bulimia Nervosa

Interventions

OTHER

Fasting state

16 hours of fasting

OTHER

Fed state

Fed a standardized meal

OTHER

Magnetic Resonance Imaging

Neuroimaging with computational modeling

Sponsors & Collaborators

Principal Investigators

  • Laura A Berner, Ph.D. · Mount Sinai Icahn School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-12-12
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05995496 on ClinicalTrials.gov