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Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty

NCT05981105 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2026-01-15

No results posted yet for this study

Summary

The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is:

1\. Is there a difference in opioid consumption 24-48 hours post block administration among patients that receive an adductor canal catheter (ACC) versus adductor canal block (ACB)?

Participants will be:

* Randomized to receive an adductor canal catheter (ACC) or a sham adductor canal catheter.
* Asked to use the Diagnotes application to communicate with the pain doctor while the catheter is in place.
* Follow up for up to 6 months post-operation. Researchers will compare the interventional group (ACC) to the control group (sham ACC + ACB) to see if there is difference in opioid consumption and chronic pain at 6 months post-operation.

Conditions

  • Chronic Pain
  • Opioid Use
  • Adductor Canal Block
  • Total Knee Arthroplasty

Interventions

DEVICE

ambIT pump with catheter

0.2% ropivacaine will be infused through a catheter pump at a rate of 10 ml/hr, 600 ml reservoir.

DEVICE

ambIT pump with sham catheter

sham catheter with no infusion

Sponsors & Collaborators

  • Hospital for Special Surgery, New York

    lead OTHER

Principal Investigators

  • Stavros Memtsoudis, MD/PhD · Hospital for Special Surgery, New York

  • Jashvant Poeran, MD/PhD · Hospital for Special Surgery, New York

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-06-12
Primary Completion
2027-01-01
Completion
2027-01-01
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05981105 on ClinicalTrials.gov