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Molecular vs Conventional Microbiologic Diagnosis for Infections in Lung Transplantation

NCT05960383 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2023-07-25

No results posted yet for this study

Summary

The goal of this prospective study is to compare rapid molecular technique BioFire Pneumonia Panel Filmarray and conventional culture-based methods in the microbiologic diagnosis on bronchoalveolar lavage of lung transplant patients.

The main questions it aims to answer are:

* determine the microbiological concordance between molecular diagnostic and conventional culture techniques on donor's bronchoalveolar lavage before lung transplantation
* determine the microbiological concordance between molecular diagnostic and conventional culture techniques on recipient's bronchoalveolar lavage, performed 72 hours after lung transplantation
* determine the microbiological concordance between molecular diagnostic and conventional culture techniques in detecting molecular resistance patterns
* determine the difference in time to microbiological results between molecular diagnostic and conventional culture techniques
* determine time to clinical decision based on molecular diagnostic techniques compared to conventional culture techniques

Conditions

Interventions

DIAGNOSTIC_TEST

BioFire Pneumonia Panel Plus

Assessment of sensbility and specificity of BioFire Pneumonia Panel Plus in lung transplantation

Sponsors & Collaborators

  • Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-02
Primary Completion
2023-10-31
Completion
2024-11-01
FDA Device
Yes

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05960383 on ClinicalTrials.gov