MedTrace Logo

Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration

NCT05957926 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2023-09-13

No results posted yet for this study

Summary

Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.

Conditions

  • Bone Loss
  • Bone Lesion

Interventions

PROCEDURE

hyaluronic acid added to hydroxyapetite

1. The procedure will be performed under complete aseptic condition, and the surgical field will be swabbed with povidone iodine solution before the operation . 2. Surgical procedure will be performed under local anesthesia (Articaine 4% with 1:100,000 adrenaline ) . 3. A full thickness mucoperiosteal flap will be reflected exposing the area of interest containing the lesion . 4. The pathological lesion will be exposed using rose head bur on low-speed handpiece under copious irrigation by normal saline . 5. The whole pathological tissues will be enucleated and sent for histopathological examination. 6. The cavity will be curetted again to remove any remaining tissues and irrigated with 0.9% normal saline . 7. hydroxyapetite with hyaluronic acid will be inserted in the bony cavity to initiate healing . 8. The flap will be repositioned and sutured with interrupted 3-0 Vicryl suture .

PROCEDURE

Hydroxyapatite alone

1. The procedure will be performed under complete aseptic condition, and the surgical field will be swabbed with povidone iodine solution before the operation . 2. Surgical procedure will be performed under local anesthesia (Articaine 4% with 1:100,000 adrenaline ) . 3. A full thickness mucoperiosteal flap will be reflected exposing the area of interest containing the lesion . 4. The pathological lesion will be exposed using rose head bur on low-speed handpiece under copious irrigation by normal saline . 5. The whole pathological tissues will be enucleated and sent for histopathological examination. 6. The cavity will be curetted again to remove any remaining tissues and irrigated with 0.9% normal saline . 7. hydroxyapetite will be inserted in the bony cavity to initiate healing . 8. The flap will be repositioned and sutured with interrupted 3-0 Vicryl suture .

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2024-08-01
Completion
2025-01-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05957926 on ClinicalTrials.gov