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Breathing and Decision-Making

NCT05936684 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 53

Last updated 2025-01-09

No results posted yet for this study

Summary

The study aims to investigate how slow breathing with prolonged exhalation (i.e., ProlEx breathing) modulates decision-making under risk in healthy participants. To do this, a short-term breathing intervention is combined with a decision-making paradigm while neural, physiological, and behavioral data are recorded.

Conditions

  • Quality of Life
  • Behavior
  • Stress, Psychological

Interventions

BEHAVIORAL

Breathing with prolonged exhalation (ProlEx) during risky decision-making

20 min divided in 3 blocks of slow, 0.1 Hz breathing (6 cycles per minute) with an inhalation-to-exhalation ratio of 2:8. Cue-assisted breathing (same across participants) and performance of a risky decision-making task (Tom et al., 2007) in the magnetic resonance imaging (MRI) scanner with simultaneous acquisition of physiological and pupil data.

BEHAVIORAL

Normal breathing (Eupnea/Control) during risky decision-making

20 min divided in 3 blocks of normal breathing (expected range: 0.16-0.33 Hz, i.e., 10-20 per min), Cue-assisted breathing (individually adapted) and performance of a risky decision-making task (Tom et al., 2007) in the MRI scanner with simultaneous acquisition of physiological and pupil data.

Sponsors & Collaborators

  • Charite University, Berlin, Germany

    collaborator OTHER

  • German Center for Diabetes Research

    collaborator OTHER

  • Freie Universität Berlin

    collaborator OTHER

  • German Institute of Human Nutrition

    lead OTHER

Principal Investigators

  • Soyoung Q Park, Prof. Dr. · German Institute of Human Nutrition

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-07-04
Primary Completion
2024-09-25
Completion
2024-09-25

Countries

  • Germany

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05936684 on ClinicalTrials.gov