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Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

NCT05909150 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2026-05-06

No results posted yet for this study

Summary

The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.

Conditions

Interventions

DRUG

Sodium chloride solution 3,5%

Patients will receive 150 mL HSS 3,5% intravenous twice daily for 3 days after heart transplantation.

DRUG

Sodium chloride solution 0,9%

Patients will receive 150 mL NS 0,9% intravenous twice daily for 3 days after heart transplantation.

Sponsors & Collaborators

  • Fernando Bacal

    lead OTHER

Principal Investigators

  • Fernando Bacal, PhD · University of Sao Paulo

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-11-08
Primary Completion
2027-03-31
Completion
2027-03-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05909150 on ClinicalTrials.gov