MedTrace Logo

CVP-guided Aquapheresis for the Treatment of Acute Congestion in Heart Failure

NCT02079259 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 9

Last updated 2015-03-17

No results posted yet for this study

Summary

The number of patients with acute congestion on chronic heart failure is increasing. Ultrafiltration has recently been proposed as an alternative approach for the stabilization of volume balance, especially in patients with imminent diuretic resistance.

There is increasing evidence that ultrafiltration may relief cardiac congestion with lesser effects on blood pressure and activation of renin angiotensin system, respectively . However, recent studies revealed conflicting results: demonstration the superiority of ultrafiltration in comparison to diuretic treatment, and a lack of evidence of benefit, as well as an excess of adverse events with ultrafiltration.

Aquapheresis with adapted ultrafiltration rate guided by central venous pressure is safer than aquaphesis with a constant ultrafiltration with comparable effectiveness

Conditions

Interventions

PROCEDURE

Ultrafiltration

Sponsors & Collaborators

  • Heinrich-Heine University, Duesseldorf

    lead OTHER

Principal Investigators

  • Ralf Westenfeld, MD · Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Dusseldorf

  • Malte Kelm, MD · Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Dusseldorf

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2014-03-31
Completion
2014-03-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02079259 on ClinicalTrials.gov