Biomarkers for Predicting the Response to Inhaled Corticosteroid in Patients With Chronic Cough.
NCT05888350 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 502
Last updated 2026-02-18
Summary
To investigate the value of blood eosinophils, FeNO and total IgE in predicting the response to inhaled corticosteroid in patients with chronic cough.
Conditions
Interventions
- DRUG
-
Beclometasone Dipropionate and Formoterol Inhalation Aerosol
Inhaled Foster (Beclometasone Dipropionate and Formoterol Inhalation Aerosol) , 1puff, BID, 4weeks
- DRUG
-
Inhaled Placebo, 1puff, BID, 4weeks
Sponsors & Collaborators
-
Huizhou Third People's Hospital
collaborator UNKNOWN -
Guangdong Provincial Hospital of Traditional Chinese Medicine
collaborator OTHER -
Nanfang Hospital, Southern Medical University
collaborator OTHER -
Shenzhen People's Hospital
collaborator OTHER -
SSL Central Hospital of Dongguan City
collaborator UNKNOWN -
China-Japan Friendship Hospital
collaborator OTHER -
Beijing Chao Yang Hospital
collaborator OTHER -
Zunyi Medical College
collaborator OTHER -
Henan Provincial People's Hospital
collaborator OTHER -
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
collaborator OTHER -
Second Hospital of Jilin University
collaborator OTHER -
Inner Mongolia People's Hospital
collaborator OTHER -
The First Affiliated Hospital of Shanxi Medical University
collaborator OTHER -
Ruijin Hospital
collaborator OTHER -
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
collaborator OTHER -
Tongji Hospital
collaborator OTHER -
First Hospital of China Medical University
collaborator OTHER -
Chongqing Songshan Hospital
collaborator UNKNOWN -
The First People's Hospital of Yunnan
collaborator OTHER -
The First Affiliated Hospital of Guangzhou Medical University
lead OTHER
Principal Investigators
-
Kefang Lai, phD · The First Affiliated Hospital of Guangzhou Medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-04-01
- Primary Completion
- 2025-04-30
- Completion
- 2025-04-30
Countries
- China
Study Locations
More Related Trials
-
A Multi-center Study to Determine the Prevalence and Influence of Pertussis on COPD Exacerbation in Shenzhen
NCT04694430 ·Status: UNKNOWN
-
Predictive Value of Inflammatory Biomarkers and FEV1 for COPD
NCT03532893 ·Status: COMPLETED
-
A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in Shenzhen
NCT04694963 ·Status: UNKNOWN
-
Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis
NCT07040332 ·Status: RECRUITING
-
A Cross-sectional Study to Measure Cough in Severe Asthma
NCT03999203 ·Status: COMPLETED ·Phase: NA
-
Effects of Environmental Fungal Exposure on Bronchial Asthma, ABPA and Bronchiectasis
NCT07313904 ·Status: RECRUITING
-
Clinical Practice of AECOPD Management in China
NCT02051166 ·Status: COMPLETED
-
Exacerbations in Severe Asthma Patients: Mechanisms and Biomarkers
NCT02660853 ·Status: COMPLETED ·Phase: NA
-
Observational Study of Sputum Inflammation Phenotypes and Clinical Outcomes in Non-Cystic Fibrosis Bronchiectasis
NCT06715956 ·Status: NOT_YET_RECRUITING
-
Multicenter Registration Study on Allergic Bronchopulmonary Aspergillosis
NCT06645210 ·Status: NOT_YET_RECRUITING
-
Treatment in Patients Hospitalized With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
NCT02219360 ·Status: UNKNOWN
-
The Utility of feNO in the Differential Diagnosis of Chronic Cough
NCT02479074 ·Status: COMPLETED ·Phase: PHASE4
-
Respiratory Pathogens of Patients With Asthma and COPD Exacerbations
NCT02866357 ·Status: COMPLETED
-
A Prospective Study of Factors Related to Exacerbation and Mortality of Non-cystic Fibrosis Bronchiectasis in Hong Kong
NCT04538859 ·Status: RECRUITING
-
A Translational Study for Prediction of Biomarkers and Identification of Phenotype and Endotype of COPD and Early COPD Outcomes in Chinese Population
NCT06724848 ·Status: RECRUITING
-
Prospective Study on the Evaluation, Patient Reported Outcomes and Effectiveness of Treatment for Chronic Cough
NCT04758351 ·Status: COMPLETED
-
Relationship Between Plasma Metabolome and the Efficacy of Systemic Glucocorticoid in AECOPD
NCT04710849 ·Status: UNKNOWN
-
Novel Inflammatory Markers in Different Phenotypes of Severe Asthma
NCT04888910 ·Status: UNKNOWN
-
Sputum and Plasma Levels of Nociceptin and Substance P in Patients With Asthma, COPD and Chronic Cough
NCT00173225 ·Status: UNKNOWN
-
A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBE
NCT07245407 ·Status: RECRUITING
-
Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath
NCT06528418 ·Status: RECRUITING
-
Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis
NCT02315547 ·Status: UNKNOWN ·Phase: NA
-
Characteristics of Postinfectious Cough
NCT06951321 ·Status: COMPLETED
-
Characterizing Asthma Sputum Elasticity in the UCSF Severe Asthma Research Program
NCT02103348 ·Status: COMPLETED
-
Research on the Characteristics of Chronic Airway Diseases (asthma, COPD)
NCT06685315 ·Status: NOT_YET_RECRUITING