Predictive Value of Inflammatory Biomarkers and FEV1 for COPD

Summary

This is a multi-center, prospective, cohort study. A total of 10,000 people aged 40～75 without lung disease will be recruited and followed for 3 years. By measure the rate of decline in forced expiratory volume at one second（FEV1） and baseline inflammatory biomarkers in exhaled breath condensate and peripheral blood, we aim to explore the predictive model for chronic obstructive pulmonary disease（COPD） in China.

Conditions

• COPD
• FEV1

Interventions

OTHER

No intervention

This is a multi-center,observational, prospective, cohort study. A total of 10,000 subjects aged 40～75 without history of lung disease will be recruited and followed for 3 years. So there is no intervention in this study.

Sponsors & Collaborators

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• Henan Provincial People's Hospital

  collaborator OTHER

• Second Hospital of Jilin University

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Shanxi Dayi Hospital

  collaborator OTHER

• Tianjin Medical University General Hospital

  collaborator OTHER

• The Affiliated Hospital of Inner Mongolia Medical University

  collaborator OTHER

• The First Hospital of Qinhuangdao

  collaborator OTHER_GOV

• Peking University First Hospital

  lead OTHER

Principal Investigators

• Guangfa Wang, MD · Peking University First Hospital

Eligibility

Min Age

40 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-03-03

Primary Completion

2020-12-31

Completion

2021-10-09

Countries

• China

Study Locations