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Impact of E-cigarette Nicotine Concentration on Compensation

NCT05887947 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2025-09-10

Study results available
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Summary

The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an explicit focus on AA and White smokers.

Conditions

  • Smoking Cessation

Interventions

DEVICE

Electronic Cigarette with 5% Nicotine Concentration

Electronic cigarette in 5% nicotine concentration (Vuse Alto), provided for free.

DEVICE

Electronic Cigarette with 1.8% Nicotine Concentration

Electronic cigarette in 1.8% nicotine concentration (Vuse Alto), provided for free.

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • University of Kansas Medical Center

    lead OTHER

Principal Investigators

  • Eleanor Leavens, PhD · University of Kansas Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-20
Primary Completion
2024-05-03
Completion
2024-06-10
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05887947 on ClinicalTrials.gov