MedTrace Logo

Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors

NCT02585791 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2020-01-14

No results posted yet for this study

Summary

This aim will examine the acute and subacute exposures to electronic cigarette (EC) vapor generated from e-liquids without nicotine (NFEC) on life-time non smokers subjects by measuring changes in nasal ion transport and TGF-β levels. Nasal ion transport will be assessed by nasal potential difference (NPD). Tumor growth factor (TGF)-β levels (mRNA and protein by ELISA) will be assessed on nasal cells and lavages.

Conditions

  • Healthy Lifetime Non-smokers

Interventions

OTHER

Propylene Glycol

inhaled Propylene Glycol (PG) by vaporing

OTHER

vegetable glycerin

inhaled vegetable glycerin (VG) by vaporing

OTHER

PG+VG

inhaled PG+VG by vaporing

Sponsors & Collaborators

  • James and Esther King Biomedical Research Program

    collaborator OTHER

  • University of Miami

    lead OTHER

Principal Investigators

  • Michael Campos, MD · University of Miami

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-02-22
Primary Completion
2019-11-11
Completion
2019-12-11

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02585791 on ClinicalTrials.gov