Deep sequencIng in Cutaneous Squamous CEll caRciNomas
NCT05878288 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 11
Last updated 2024-11-21
Summary
To comprehensively describe the molecular profile of the tumour ecosystem of cutaneous squamous cell carcinoma (CSCC) patients treated with neoadjuvant immunotherapy using single-cell sequencing and bulk genomic profiling.
Conditions
- Cutaneous Squamous Cell Carcinoma
- Cutaneous Squamous Cell Carcinoma of the Head and Neck
- Neoplasms
- Non-melanoma Skin Cancer
Interventions
- DRUG
-
Cemiplimab 50 mg/mL supplied as a sterile liquid in single-use glass vials.
Sponsors & Collaborators
- collaborator OTHER
-
University of Adelaide
collaborator OTHER - collaborator OTHER
- collaborator INDUSTRY
- collaborator INDUSTRY
-
Peter MacCallum Cancer Centre, Australia
lead OTHER
Principal Investigators
-
Annette M Lim, MBBS, FRACP, PhD · Peter MacCallum Cancer Centre, Australia
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-26
- Primary Completion
- 2029-05-31
- Completion
- 2029-05-31
Countries
- Australia
Study Locations
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