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Age-dependent Effects of Smoked and Oral Delta-9-THC

NCT05865470 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 103

Last updated 2026-01-07

No results posted yet for this study

Summary

This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.

Conditions

  • Pain
  • Abuse, Drug
  • Intoxication; Cannabinoids

Interventions

DRUG

Cannabis

smoked cannabis

DRUG

Dronabinol

Oral delta-9-THC

DRUG

Smoked Placebo

Placebo Cannabis

DRUG

Oral Placebo

Oral Placebo

Sponsors & Collaborators

Principal Investigators

  • Ziva Cooper, PhD · University of California, Los Angeles

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-30
Primary Completion
2028-10-15
Completion
2029-10-15
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05865470 on ClinicalTrials.gov