Analgesic and Subjective Effects of Terpenes

Summary

The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.

Conditions

• Pain
• Abuse, Drug

Interventions

DRUG

Low THC

Vaporized THC (5 mg)

DRUG

High THC

Vaporized THC (15 mg)

DRUG

Low Myrcene

Vaporized Myrcene (0.5 mg)

DRUG

High Myrcene

Vaporized Myrcene (12.0 mg)

DRUG

Low Beta-Caryophyllene

Vaporized Beta-Caryophyllene (0.5 mg)

DRUG

High Beta-Caryophyllene

Vaporized Beta-Caryophyllene (7.5 mg)

DRUG

Placebo

Vaporized Placebo

Sponsors & Collaborators

• National Center for Complementary and Integrative Health (NCCIH)

  collaborator NIH

• University of California, Los Angeles

  lead OTHER

Principal Investigators

• Ziva Cooper, PhD · University of California, Los Angeles

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Model

CROSSOVER

Eligibility

Min Age

21 Years

Max Age

55 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-12-15

Primary Completion

2025-11-12

Completion

2026-07-30

FDA Drug

Yes

Countries

• United States

Study Locations