Human Phenotype Project Study Protocol
NCT05817734 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30000
Last updated 2024-07-16
Summary
This is a prospective study aimed at recruiting 30,000 individuals, aged 40-70 years old, and following them longitudinally for 25 years with repeated measurements. The basic follow-up frame will include a visit to the Clinical Test Center (CTC) every two years and a phone interview every other year (on uneven years). Sample collection and biobanking will be performed every two years and online questionnaires will be filled out on an annual basis.
The primary goals are to study the variation observed across different individuals in disease susceptibility, clinical phenotypes, and therapeutic responses. The study aims at studying the complex interplay and relative contribution of different omics, physiological characteristics and lifestyle on disease pathogenesis and progression and to evaluate how these effects are mediated.
Conditions
- Adult Disease
Sponsors & Collaborators
-
Weizmann Institute of Science
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-10-01
- Primary Completion
- 2045-12-31
- Completion
- 2045-12-31
Countries
- Israel
Study Locations
More Related Trials
-
Epidemiology of Acute Phase Protein and CHD
NCT00005371 ·Status: COMPLETED
-
Mayo Clinic Precure - Prospective Study
NCT07332598 ·Status: ENROLLING_BY_INVITATION
-
Development, Testing, and Validation of A Protocol To Assess Cardiovascular Reactivity in Human Populations
NCT00005231 ·Status: COMPLETED
-
Epidemiology of Decline in Heart Disease Mortality
NCT00005162 ·Status: COMPLETED
-
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
NCT02543996 ·Status: RECRUITING
-
Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers
NCT03038750 ·Status: TERMINATED
-
Proteomics and Genomics Combined With CT to Predict CVD
NCT05800093 ·Status: ACTIVE_NOT_RECRUITING
-
HYPGENE-Genetics Fitness Obesity & Risk of Hypertension
NCT00083811 ·Status: COMPLETED
-
COV2Base-A Rare Disease by COVID Study
NCT04564274 ·Status: COMPLETED
-
Identification of Heritable CTEPH
NCT03579862 ·Status: UNKNOWN
-
Biomarkers of Oxidative Stress in LOOK AHEAD - Ancillary to LOOK AHEAD
NCT00031226 ·Status: COMPLETED
-
The Longevity Genes in Founder Populations Project
NCT00707694 ·Status: RECRUITING
-
Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasE
NCT05357404 ·Status: ACTIVE_NOT_RECRUITING
-
Predictive Medicine Research
NCT00384761 ·Status: COMPLETED
-
Identification of Genes Expressed in Atherosclerotic Plaque
NCT00353730 ·Status: COMPLETED
-
Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells
NCT01517425 ·Status: ENROLLING_BY_INVITATION
-
Health Promotion in the Elderly--Prevention of Cardiovascular Disorders
NCT00005450 ·Status: COMPLETED
-
Mortality Surveillance of MRFIT Screenees
NCT00005156 ·Status: COMPLETED
-
Epidemiology of Cardiovascular Diseases in The Elderly
NCT00005186 ·Status: COMPLETED
-
Genomewide Search for Loci Underlying Metabolic Syndrome
NCT00074451 ·Status: COMPLETED
-
The Implementation of Pharmacogenomics Into Primary Care in British Columbia
NCT02383290 ·Status: COMPLETED ·Phase: NA
-
Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
NCT01117506 ·Status: COMPLETED
-
Epidemiology of Carotid Disease in Elderly Adults
NCT00005230 ·Status: COMPLETED
-
Study of Protein Translocation in Patients With Beta-Oxidation Disorders
NCT00004348 ·Status: COMPLETED
-
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health
NCT05819814 ·Status: RECRUITING ·Phase: NA