The Implementation of Pharmacogenomics Into Primary Care in British Columbia

Summary

Certain parts of the gene can predict how an individual person will respond to medication (pharmacogenetics). We will invite 250 individuals to give a sample of saliva. This sample will be sent to a laboratory for limited genomic analysis relating to pharmacogenetics. When personal data held by the participants, family physician, or pharmacist is joined with the genetic data personalized prescription recommendations are formed. The family physicians/pharmacists can view these recommendations through their electronic record. This should result in prescriptions that may be more beneficial and cause fewer adverse events.

Conditions

• Pharmacogenetics

Interventions

OTHER

Decision support

Saliva samples will be collected from each participant for genetic testing. A genetic report will be fed back to the research server, and into the Family Physicians/pharmacist's electronic record. The electronic record is linked to the UBC TreatGx computer; the next time the participant is seen by the Family Physician / Pharmacist personalized prescribing recommendations will be available for use.

Sponsors & Collaborators

• Genome British Columbia

  collaborator INDUSTRY

• Pfizer

  collaborator INDUSTRY

• Merck Sharp & Dohme LLC

  collaborator INDUSTRY

• Roche Pharma AG

  collaborator INDUSTRY

• GlaxoSmithKline

  collaborator INDUSTRY

• AstraZeneca

  collaborator INDUSTRY

• Health Research Foundation

  collaborator OTHER

• Janssen, LP

  collaborator INDUSTRY

• University of British Columbia

  lead OTHER

Study Design

Allocation

NA

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-04-30

Primary Completion

2015-10-31

Completion

2015-12-31