Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study
NCT05811312 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2025-06-17
Summary
This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The investigators will enroll Veterans who are currently receiving care at the Medical Center and who are either long term users of SCS for the treatment of their chronic pain or being evaluated for use of SCS to treat their pain.
Conditions
- Neuropathic Pain
Sponsors & Collaborators
-
VA Office of Research and Development
lead FED
Principal Investigators
-
Svetlana Pundik, MD · Louis Stokes VA Medical Center, Cleveland, OH
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-01
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
More Related Trials
-
Brain Activity in People With Chronic Neuropathic Pain and Spinal Cord Injury
NCT04386174 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Spinal Functional Magnetic Resonance Imagine (fMRI) Study of Resting-State, Motor Task and Acupoint Stimulation
NCT00629655 ·Status: COMPLETED
-
Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals
NCT05303428 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals
NCT05303415 ·Status: RECRUITING ·Phase: NA
-
Magnetic Resonance Imaging of the Brain in Emotional Processing
NCT00061204 ·Status: COMPLETED
-
Combining fMRI and tDCS in Neuropathic Pain
NCT06237075 ·Status: RECRUITING ·Phase: NA
-
Targeting Large-scale Networks in Depression With Real-time fMRI (Functional Magnetic Resonance Imaging) Neurofeedback
NCT05934604 ·Status: COMPLETED ·Phase: NA
-
Transcranial Magnetic Stimulation for Facial Pain
NCT02633306 ·Status: COMPLETED ·Phase: NA
-
Stimulation-Induced Changes in Fronto-Limbic Network
NCT05854160 ·Status: RECRUITING ·Phase: NA
-
Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning
NCT06234917 ·Status: COMPLETED ·Phase: NA
-
Human Brain Mapping of the Apparent Diffusion Coefficient (ADC) During Sleep and Wakefulness
NCT02311374 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Neurofeedback Treatment of Pain in Persons With Spinal Cord Injury (SCI)
NCT00947999 ·Status: COMPLETED
-
Structural and Functional Brain Reorganization in Neuropathic Pain: Basal State of Local Cerebral Blood Flow and Functional Connectivity
NCT02858466 ·Status: TERMINATED ·Phase: NA
-
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain
NCT03003715 ·Status: COMPLETED ·Phase: NA
-
Brain Network fMRI Analysis in Proprioceptive Training for Chronic Low Back Pain
NCT07308249 ·Status: NOT_YET_RECRUITING
-
MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI
NCT00561782 ·Status: COMPLETED
-
Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
NCT00388414 ·Status: COMPLETED ·Phase: NA
-
Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort
NCT06472622 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Synaptic Injury and Functional Connectivity in Alzheimer's Disease
NCT03300726 ·Status: COMPLETED
-
EEG-fMRI: Towards a Useful Clinical Tool in Epilepsy
NCT02410889 ·Status: COMPLETED
-
Descriptive Pilot Study of the Effects of a Standardized Neuromodulation Program on Cortical Brain Function in Chronic Low Back Pain Patients
NCT03929952 ·Status: COMPLETED ·Phase: NA
-
Studying Motor Neuron Tests
NCT01517087 ·Status: COMPLETED
-
Combined Cingulate and Thalamic DBS for Chronic Refractory Chronic Pain
NCT03399942 ·Status: COMPLETED ·Phase: NA
-
Ketamine and fMRI for Neuropathic Pain
NCT02373449 ·Status: COMPLETED ·Phase: NA
-
Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
NCT02629107 ·Status: RECRUITING