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Time-In-Range Based Risk Stratification of Type 2 Diabetes Microvascular Complications

NCT05787990 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-04-07

No results posted yet for this study

Summary

The goal of this observational study is to learn about the role of Time-in-Range to stratify the risk of micro vascular complications in adults with type 2 diabetes. The main questions it aims to answer are:

1. Is a lower Time-in-Range associated with a higher risk of diabetes microvascular complications, independent of HbA1c?
2. Is Time-in-Range lower among sulfonylurea and premixed insulin therapy users compared to non-sulfonylurea and non-premixed insulin therapy users, respectively.

Conditions

  • Type 2 Diabetes
  • Diabetes Related Complications
  • Diabetes; Retinopathy (Manifestation)
  • Diabetes; Neuropathy, Polyneuropathy (Manifestation)
  • Diabetes; Nephropathy (Manifestation)

Interventions

DIAGNOSTIC_TEST

Diabetes Microvascular Complication Tests

Continuous glucose monitoring using Freestyle Libre Pro, Foot examination with monofilament and neurothesiometer, HbA1c and Urine Microalbumin Creatinine Ratio, Corneal confocal microscopy, Fundal photography, Optical coherence tomography, Optical cohere

Sponsors & Collaborators

  • Singapore Eye Research Institute

    collaborator OTHER

  • Singapore General Hospital

    lead OTHER

Principal Investigators

  • Suresh Rama Chandran, MD, MRCP(UK) · Singapore General Hospital

Eligibility

Min Age
21 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-14
Primary Completion
2024-06-30
Completion
2024-12-31

Countries

  • Singapore

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05787990 on ClinicalTrials.gov