MedTrace Logo

Analysis of the Aetiological Factors of Malnutrition

NCT05781178 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 271

Last updated 2024-09-19

No results posted yet for this study

Summary

Disease-related malnutrition (DRM) is a frequent syndrome in clinical practice, in which the mutual relationship between disease and malnutrition is observed. Inflammation, anorexia, changes in body composition or in energy and protein requirements, contribute to the development of DRM. The Global Leadership Initiative on Malnutrition (GLIM criteria) provides a diagnostic system of malnutrition that has been accepted by the main international scientific societies in the field of clinical nutrition.

The GLIM criteria proposes an algorithm that includes phenotypic criteria (weight loss, underweight and low muscle mass), with their corresponding severity thresholds, and aetiological criteria (decreased oral intake, nutrient malabsorption and the presence of an inflammatory component). The diagnosis of malnutrition is established when an aetiological and a phenotypic criterion are met.

The aim of the study is to determine the diagnostic and prognostic value of aetiological factors of malnutrition based on GLIM criteria, presence and degree of inflammation and dietary intake, in patients diagnosed with DRM.

Conditions

Interventions

DIETARY_SUPPLEMENT

Oral nutritional supplement rich in omega-3 and olive oil polyphenols

Nutritional intervention with an oral nutrition supplement with anti-inflammatory effect and a programme of physical exercise

Sponsors & Collaborators

  • Adventia Pharma

    collaborator INDUSTRY

  • Endocrinology and Clinical Nutrition Research Center, Spain

    lead OTHER

Principal Investigators

  • Daniel de Luis Roman, Prof · Endocrinology and Nutrition Department. Hospital Clínico Universitario de Valladolid (Spain)

  • Samara Palma Milla, PhD · Endocrinology and Nutrition Department. Hospital Universitario La Paz (Spain)

  • Alfonso Vidal Casariego, PhD · Endocrinology and Nutrition Department. Complejo Hospitalario Universitario de A Coruña (Spain)

  • José M García Almeida, PhD · Endocrniology and Nutrition Department. Hospital Universitario Virgen de la Victoria (Spain)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-02
Primary Completion
2024-05-17
Completion
2024-09-11

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05781178 on ClinicalTrials.gov