Mobilization With Movement (MWM) on Knee Osteoarthritis (OA)

Summary

Movement with mobilization (MWM) is an effective manual therapy to improve pain and function of patients with knee osteoarthritis (OA).

However, immediate, and prolonged effects after prolonged MWM period was under-investigated.

In this double-blinded randomized control trial, 40 patients are needed. The subjects and assessors will be blinded. Subjects in intervention group will receive MWM twice a week and corresponding home exercise for 6 weeks.

Participants in control group will only receive sham treatment with light touch.

The effects on knee pain in visual analogue scale (VAS); flexion and extension range of motion (ROM) by goniometer; strength by hand-held dynamometer; function by Timed Up and Go Test (TUG) and 30-second Chair Stand Test; and health-related quality of life (HRQoL) by Knee Injury and Osteoarthritis Outcome Score (KOOS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) just after, 1-month and 3-month after treatment will be compared with baseline. Six-month after treatment, KOOS and WOMAC will be conducted.

Conditions

• Knee Osteoarthritis

Interventions

OTHER

Movement with Mobilization (MWM)

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior glide, is applied to the knee of the patient. Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

OTHER

Sham Movement with Mobilization (Sham MWM)

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior light-touch glide, is applied to the knee of the patient. Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Sponsors & Collaborators

• The Hong Kong Polytechnic University

  lead OTHER

Principal Investigators

• KING HIM CHAN, BSc · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

• MING HON LEE, BSc · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

• YIK SING SHUM, BSc · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

• YEUK LAI CHAN, BSc · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

• FADI AL ZOUBI, PhD · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

• MAN HA TSANG, PhD · Department of Rehabilitation Sciences, The Hong Kong Polytechnic University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

40 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-12-10

Primary Completion

2023-05-10

Completion

2023-05-10

Countries

• Hong Kong

Study Locations