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Retinal Vascular Changes in Patients After Coronavirus Disease 2019 (COVID-19)

NCT05747547 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2025-05-29

No results posted yet for this study

Summary

The study examines changes in retinal oximetry in patients after COVID-19 disease. It aims to analyze and quantify possible retinal microvascular abnormalities that may result from possible post-inflammatory damage to the endothelium of the vessels associated with COVID-19 disease. Retinal vascular involvement may indicate similar changes in the vascular system in other organs.

Conditions

Interventions

DIAGNOSTIC_TEST

Central visual acuity

Measurement of central visual acuity using ETDRS (Early Treatment Diabetic Retinopathy Study) optotypes or Snellen optotype chart.

DIAGNOSTIC_TEST

Intraocular pressure measurement

Measurement of intraocular pressure using non-contact Canon TX-20P tonometer.

DIAGNOSTIC_TEST

Slit lamp examination

Slit lamp examination of the anterior and posterior segment of the eye after pharmacological dilation of the pupil using application of short-time mydriatics (1% tropicamide and 10% phenylephrine).

DIAGNOSTIC_TEST

Retinal oximetry

Performing of retinal oximetry with an Oxymap T1 instrument (Oxymap ehf.) paired with a Topcon TRC-50DX retinal camera.

DIAGNOSTIC_TEST

Optical coherence tomography and angiography

Performing of optical coherence tomography and angiography with the Spectralis Optical Coherence Tomography Plus (Heidelberg Engineering).

Sponsors & Collaborators

  • Palacky University

    collaborator OTHER

  • University Hospital Olomouc

    lead OTHER

Principal Investigators

  • Zuzana Schreiberova, MD · University Hospital Olomouc and Palacky University Olomouc

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-01
Primary Completion
2023-05-01
Completion
2024-10-01

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05747547 on ClinicalTrials.gov