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Diabetic Retinopathy and Subclinical Signs of Disease Transition

NCT03635671 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 5

Last updated 2019-08-29

No results posted yet for this study

Summary

The prevalence of diabetes mellitus (DM) is increasing worldwide. Diabetic retinopathy is the most prevalent complication of DM and a leading cause of visual impairment. Some factors are known to temporarily aggravate or improve diabetic retinopathy, but underlying pathophysiologic factors are still unknown. High-resolution imaging techniques of the retina and its supplying vascular networks now allow novel insight to subtle changes that cannot be appreciated in standard fundus examination. In detail, the investigators image study patients with optical coherence tomography (OCT) - technology, that provides morphological information of retinal structure and the supplying vessels in a non-invasive way. Retinal layer thickness as well as capillary density will be quantified and followed in patients that are in a critical period of disease transition to better understand the process of diabetic retinopathy.

Conditions

Interventions

DIAGNOSTIC_TEST

Optical Coherence Tomography Angiography

Retinal scans will be acquired at each follow up visit

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • David Maberley, MD · Head of the Department of Ophthalmology and Visual Science, UBC

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2019-07-15
Completion
2019-07-15

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03635671 on ClinicalTrials.gov