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Study on the Relationship Between Iodine Nutrition and Thyroid Diseases in the Elderly

NCT05716191 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2023-08-16

No results posted yet for this study

Summary

The aging trend of China's population is intensifying. More than 50% of the elderly in China suffer from thyroid disease. Thyroid dysfunction in the elderly increases the risk of cardiovascular and metabolic diseases. Even if thyroid-stimulating hormone (TSH) is within the normal range, brain atrophy and infarction-like vascular damage in elderly males will be aggravated with the increased TSH level. Iodine is an essential component of thyroid hormones. Iodine deficiency or excess may lead to a series of thyroid diseases. The risk threshold of iodine intake in the elderly is unknown. The goal of this observational study is to clarify the relationship between thyroid diseases and iodine intake in the elderly. The aims are:

1. to clarify the differences in the prevalence of thyroid diseases in the elderly with different iodine nutrition backgrounds.
2. to analyze the effects of mild iodine deficiency and iodine excess on the thyroid health of the elderly.
3. to explore the hazard threshold of iodine intake for old people.
4. to compare the differences in thyroid disease and iodine nutritional status between young and middle-aged people and old people.

Conditions

  • Nutrition, Healthy
  • Elderly

Interventions

OTHER

Naturally different iodine levels exposure

A cross-sectional survey of thyroid disease in elderly people in areas with different iodine nutrition backgrounds

Sponsors & Collaborators

  • Tianjin Medical University General Hospital

    collaborator OTHER

  • Shandong Provincial Institute for Endemic Disease Control

    collaborator UNKNOWN

  • Tianjin Medical University

    lead OTHER

Principal Investigators

  • Wenxing Guo, Doctor · Public Health School, Tianjin Medical University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-17
Primary Completion
2025-06-01
Completion
2025-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05716191 on ClinicalTrials.gov