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Research on Association Between Selenium Deficiencies and Change of Thyroid Function

NCT03448588 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2018-05-23

No results posted yet for this study

Summary

As one of the essential micronutrients, selenium has important biological functions. However, an effective and convenient method for evaluation of selenium nutritional status has not yet been established. Previous literature has disclosed effect of selenium deficiency on inactivating glutathion peroxidase and deiodinase, which may cause decreased conversion from thyroxine ( T4) to triiodothyronine (T3). A case-control study is designed to demonstrate the association between selenium deficiency and abnormally elevated T4 or T4/T3, which may provide more clues for establishing effective selenium assesment methods.

Conditions

  • Selenium Deficiency

Interventions

DIAGNOSTIC_TEST

detection of serum selenium

For this case-control study, no intervention will be administered to participants, only serum sample will be collected for selenium assessment

Sponsors & Collaborators

  • Peking Union Medical College Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-04-01
Primary Completion
2018-12-31
Completion
2019-04-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03448588 on ClinicalTrials.gov