Thyroid Disorders in Malaysia: A Nationwide Multicentre Study

Summary

This will be a population based study looking at the prevalence of thyroid disorders in Malaysia (including hypo- and hyperthyroidism, subclinical hypo- or hyperthyroidism) and its association with different ethnicity and iodine status. The study will also look at genetic susceptibility for autoimmune thyroid disorders in the Malaysian population

General hypotheses:

The prevalence of thyroid disorders in Malaysia is 10% for hypothyroidism and 2% for hyperthyroidism Hypo- and hyperthyroidism is associated with iodine status in our population There are different susceptibility gene for autoimmune thyroid disorder in different ethnicity in our population

Conditions

• Hypothyroidism
• Subclinical Hypothyroidism
• Hyperthyroidism
• Subclinical Hyperthyroidism
• Graves Disease
• Hashimoto's Thyroiditis
• Iodine Deficiency
• Genetic Susceptibility

Sponsors & Collaborators

• Malaysian Endocrine and Metabolic Society

  collaborator OTHER

• National University of Malaysia

  collaborator OTHER

• University of Malaya

  collaborator OTHER

• IMU University, Malaysia

  collaborator OTHER

• International Islamic University Malaysia

  lead OTHER

Principal Investigators

• Nor Azmi Kamaruddin, MBBS, MMed · National University of Malaysia

• Norlela Sukor, MMed, Phd · National University of Malaysia

• Norhanita Othman · National University of Malaysia

• Johari Ali · University of Malaya

• Shirenee Vethakkan · University of Malaya

• Siew Kim Kwa · IMU University, Malaysia

• Kuck Meng Chong, MD · Malaysian Endocrine and Metabolic Society

• Lecthuman Ramanathan · Malaysian Endocrine and Metabolic Society

• Hussein Zanariah · Malaysian Endocrine and Metabolic Society

• Nurain Mohd Noor · Malaysian Endocrine and Metabolic Society

• Norhaliza Mohd Ali · Malaysian Endocrine and Metabolic Society

• Norhayati Yahya · Malaysian Endocrine and Metabolic Society

• Nor Azizah Aziz · Malaysian Endocrine and Metabolic Society

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2014-08-31

Primary Completion

2016-09-30

Completion

2016-09-30