MedTrace Logo

Peripheral Treg Cell Senescence & Serum Total Cholesterol Level

NCT05680844 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-04-08

No results posted yet for this study

Summary

Hypercholesterolemia is a risk factor for the occurrence and development of atherosclerosis. Recent animal studies have found that increased serum cholesterol level is associated with peripheral Treg cell senescence, but clinical evidence is still lacking. The purpose of this study is to analyze the correlation between human peripheral Treg cell senescence and serum total cholesterol level using clinical blood samples, thus laying a foundation for the establishment of novel therapeutic strategies for atherosclerosis based on the regulation of Treg cell senescence.

Conditions

Sponsors & Collaborators

  • Tianjin Medical University

    lead OTHER

Principal Investigators

  • Ping Lei, Ph.D. · Tianjin Medical University General Hospital

Eligibility

Min Age
30 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-12-31
Completion
2024-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05680844 on ClinicalTrials.gov