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Neural Correlates of Acute Pain Dynamics

NCT05669924 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2024-05-01

No results posted yet for this study

Summary

This work aims to study the neural correlates and determinants of pain dynamics related to changes in a noxious stimulus.

Conditions

Interventions

DRUG

Methylphenidate

0.35 mg/kg methylphenidate will be administered after baseline testing and 45 min-1 hr before post-intervention testing.

DRUG

Placebo

Placebo for methylphenidate

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH

  • Northwestern University

    lead OTHER

Principal Investigators

  • Andrew D Vigotsky, MS · Northwestern University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-09-19
Primary Completion
2024-04-26
Completion
2024-04-26
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05669924 on ClinicalTrials.gov