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Motivation and Methylphenidate

NCT03190681 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2026-04-24

No results posted yet for this study

Summary

The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.

Conditions

  • Motivation
  • Apathy
  • Impulsive Behavior

Interventions

DRUG

Ritalin (methylphenidate)10Mg Tablet

oral ingestion of 3 tablets in a single-dose

DRUG

Placebo Oral Tablet

oral ingestion of 3 tablets in a single-dose

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-07-11
Primary Completion
2017-11-15
Completion
2017-11-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03190681 on ClinicalTrials.gov