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Efficacy and Safety of Painless 5-aminolevulinic Acid Photodynamic Therapy for Moderate and Severe Acne Vulgaris

NCT04167982 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 234

Last updated 2020-11-24

No results posted yet for this study

Summary

This study is being done to compare a new, continuous illumination and short Incubation time regimen of 5-aminolevulinic acid photodynamic therapy (painless ALA- PDT) to low-dose and conventional dose of oral isotretinoin for treatment of moderate or severe acne vulgaris. The hypothesis is that the painless ALA- PDT will be equally or more efficacious as oral isotretinoin, and taking effect more quickly with less adverse effect.

Conditions

Interventions

PROCEDURE

Aminolevulinic acid photodynamic therapy

Aminolevulinic acid photodynamic therapy

DRUG

Oral conventional-dose isotretinoin

Conventional-dose isotretinoin

DRUG

Oral low-dose isotretinoin

low-dose isotretinoin

Sponsors & Collaborators

  • Huadong Hospital

    collaborator OTHER

  • RenJi Hospital

    collaborator OTHER

  • Shanghai Dermatology Hospital

    lead OTHER

Principal Investigators

  • Xiuli Wang, MD PhD · Shanghai Skin Disease Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-28
Primary Completion
2022-11-30
Completion
2022-11-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04167982 on ClinicalTrials.gov