A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients

Summary

This multicenter retrospectively observational cohort study was conducted on participants with histologically confirmed gastric and colorectal cancer who underwent radical surgery in 11 medical centers in China from August 1, 2015, to June 31, 2018. Baseline clinicopathologic data and nutritional status assessments including Nutrition Risk Screening 2002 (NRS 2002) score and Patient-generated Subjective Global Assessment (PG-SGA) rating were collected. Variables will be screened using the least absolute shrinkage and selection operator (LASSO) regression model and Cox regression analysis. Internal and external validations will be performed via the receiver operating curve (ROC), the area under the curve (AUC), the concordance index (C-index), calibration plots, decision curve analysis (DCA), and Five folds cross-validation by 200 times.

Conditions

• Gastrointestinal Cancers - Stomach
• Gastrointestinal Cancers - Colorectal
• Prognosis
• Survival Analysis
• Nutrition Assessment

Interventions

OTHER

observation

There are no interventions.

Sponsors & Collaborators

• Jiangsu Cancer Institute & Hospital

  collaborator OTHER

• Xijing Hospital

  collaborator OTHER

• Northern Jiangsu People's Hospital

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  collaborator OTHER

• Shanghai 10th People's Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• First Affiliated Hospital of Kunming Medical University

  collaborator OTHER

• The Second Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• Peking Union Medical College Hospital

  collaborator OTHER

• Chinese PLA General Hospital

  collaborator OTHER

• Wang Xinying

  lead OTHER

Principal Investigators

• Xinying Wang, M.D. · Jinling Hospital, China

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-11-10

Primary Completion

2022-11-25

Completion

2022-11-25

Countries

• China

Study Locations