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The Effect of an Acute Bout of Exercise on Pain Sensitivity and Clinical Pain in Adults With Knee Osteoarthritis

NCT05605444 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2025-08-28

No results posted yet for this study

Summary

The goal of this interventional study is to investigate the effectiveness of an acute bout of exercises on pain sensitivity and clinical pain among adults with knee osteoarthritis. The following question will be answered in this research Q1: Is acute bout of exercise effective in reducing pain sensitivity and intensity among adult with knee osteoarthritis?

Participants who agree to participate and sign the informed consent will be randomised to one of three groups:

Group 1: Isometric exercise with neutral language and no verbal suggestion consisting of 1 rep of wall squat, 3 min or to volitional fatigue at 100° knee angle;(n=30).

Group 2: Isometric exercise with neutral language and no verbal suggestion consisting of 3 reps of wall squat, 3 min or to volitional fatigue at 100°degree knee angle, 30 sec rest between rep, ;(n=30).

Group 3 (Control group): true control (do nothing);(n=30).

Conditions

  • Osteoarthritis, Knee

Interventions

OTHER

Single bout of exercise

isometric wall squat at a knee joint angle of 100 degrees. Instruct participant to place their back against the wall with feet positioned parallel and spaced shoulder-width apart. Lower themselves down until they reached a knee joint angle of 100 degrees. Measure knee joint angle by placing a goniometer on the lateral epicondyle of the knee, in line with the femur whilst the anchor arm was in line with the lateral malleolus.

Sponsors & Collaborators

  • Taif University

    lead OTHER

Principal Investigators

  • Hosam Alzahrani, PhD · Taif University, College of Applied Medical Science, Physical Therapy Department, TAIF, SAUDI ARABIA

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-15
Primary Completion
2023-04-25
Completion
2023-05-20

Countries

  • Saudi Arabia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05605444 on ClinicalTrials.gov