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Relationship of EBV-positive Gastric Cancer and Multiple Genes Associated With Gastric Carcinogenesis

NCT05604378 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 460

Last updated 2022-11-03

No results posted yet for this study

Summary

The data of 460 gastric cancer patients who underwent curative gastrectomy with D2 lymph node dissection between January 2017 and February 2022 were analyzed. The clinicopathological features and prognosis of the patients with EBV-positive gastric cancers were compared with those of EBV-negative gastric cancers. Immunohistochemistry for epidermal growth factor receptor (EGFR), C-erb B2, Ki-67, and p53 was performed. Additionally, in situ hybridization was conducted to detect EBV, and microsatellite instability (MSI) analysis was used to assess the deficiency in mismatch repair (MMR) genes.

Conditions

Interventions

PROCEDURE

Gastrectomy

All patients in our study underwent gastrectomy.

Sponsors & Collaborators

  • Saint Vincent's Hospital, Korea

    lead OTHER

Principal Investigators

  • Kyong Hwa Jun, Ph.D. · The Catholic University of Korea

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-03
Primary Completion
2022-10-28
Completion
2022-10-28

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05604378 on ClinicalTrials.gov