Investigation of the Proportion of Human Epidermal Growth Factor Receptor 2 Protein Overexpression of Gastric Adenocarcinoma and Prognostic Effect of HER2, and Analysis of Practice Pattern of Herceptin Use in Stage IV Gastric Cancer
NCT02136836 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 860
Last updated 2014-05-13
Summary
The objective of this study is to investigate the proportion of HER2 overexpression in gastric cancer patients group, to evaluate the relation of HER2 overexpression with prognosis, and to analyze the proportion of herceptin applied to patients in clinical field. Furthermore, the investigators are going to reevaluate the clinical benefit of Herceptin for survival prolongation compared to chemotherapy only.
Conditions
- Stomach Neoplasms
Sponsors & Collaborators
-
Yonsei University
lead OTHER
Principal Investigators
-
Jae Yong Cho, M.D.,Ph.D. · Gangnam Severance Hospital, Yonsei University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-05-31
- Primary Completion
- 2015-03-31
Countries
- South Korea
Study Locations
More Related Trials
-
Perioperative Chemotherapy With Herceptin For Potentially Resectable HER-2 Positive Gastric Cancer With Liver Metastasis
NCT02380131 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study of Herceptin (Trastuzumab) in Combination With Cisplatin/Capecitabine Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer
NCT01450696 ·Status: TERMINATED ·Phase: PHASE3
-
The Clinical Study of Assessing HER-2 Expression in Gastric Cancer With Extra Tumor Tissue Paraffin Blocks Using Immunohistochemistry
NCT02843412 ·Status: UNKNOWN
-
HER2-positive Locally Advanced/Metastatic Gastric and/or Gastroesophageal Junction (GEJ) Adenocarcinoma in Russia
NCT05892926 ·Status: COMPLETED
-
A Comparative Study of Salvage Treatment With Combination of Docetaxel and Epirubicin
NCT01624025 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab in HER2-positive Biliary Tract Cancer
NCT03613168 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab Based Therapy in HER2 Positive AGC
NCT03024450 ·Status: COMPLETED
-
A Study to Investigate the Efficacy and Safety of ONO-4578 in Combination With Nivolumab and Chemotherapy in Chemotherapy-naïve Participants With HER2-negative Unresectable Advanced or Recurrent Gastric Cancer (Including Esophagogastric Junction Cancer)
NCT06256328 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of DP303c Injection in Patients With Advanced or Metastatic Gastric Cancer
NCT04826107 ·Status: UNKNOWN ·Phase: PHASE2
-
Lauren Classifications and HER2 Status in Gastric Cancer Patients
NCT01927146 ·Status: UNKNOWN
-
A Study of Herceptin (Trastuzumab) in Combination With Standard Chemotherapy in Patients With HER Positive Metastatic Gastric Cancer
NCT01260194 ·Status: TERMINATED ·Phase: PHASE4
-
PF-00299804 Monotherapy in Patients With HER-2 Positive Advance Gastric Cancer
NCT01152853 ·Status: COMPLETED ·Phase: PHASE2
-
Her 2 Testing in Indian Patients With Gastric Cancer
NCT01814345 ·Status: TERMINATED
-
A Phase II Study of Irinotecan, Oxaliplatin, Plus TS-1 in Untreated Metastatic Gastric Cancer
NCT00512681 ·Status: COMPLETED ·Phase: PHASE2
-
HER2 Positive CTC in Advanced Gastric Cancer
NCT01847794 ·Status: UNKNOWN ·Phase: NA
-
Study of Afuresertib Combined With Paclitaxel in Gastric Cancer
NCT02240212 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Herceptin (Trastuzumab) in Patients With Metastatic or Advanced Gastric Cancer With Disease Progression
NCT02005484 ·Status: TERMINATED ·Phase: PHASE2
-
Trastuzumab to Patients With Advanced Gastric Cancer With HER2 Positive Expression in CTC
NCT04168931 ·Status: TERMINATED ·Phase: PHASE2
-
BReast CAncer Genes(BRCA) Expressions in Metastatic Gastric Cancer
NCT03838406 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Family (EGFR, HER2, HER3, HER4) Mutations or HER2 Amplification/Overexpression
NCT05512182 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Non-Interventional Study of Treatment Pattern and Clinical Outcomes in Chinese Participants With Gastric Cancer
NCT01839500 ·Status: COMPLETED
-
Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX
NCT01396707 ·Status: COMPLETED ·Phase: PHASE2
-
Concurrent Neoadjuvant Chemoradiotherapy Plus Trastuzumab in the Treatment of Siewert II ,III of Human Epidermal Growth Factor Receptor-2(HER-2) Positive Gastroesophageal Junction Adenocarcinoma: A Randomized, Controlled Clinical Study
NCT03368131 ·Status: UNKNOWN ·Phase: PHASE2
-
Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System
NCT03185988 ·Status: UNKNOWN ·Phase: PHASE2
-
Weekly Docetaxel/Irinotecan for Non-resectable Gastric Cancers After Cisplatin Plus 5-FU/Leucovorin
NCT00166881 ·Status: COMPLETED ·Phase: PHASE2