Predicting Biomarker of Gastric Cancer Chemotherapy Response
NCT03253107 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800
Last updated 2023-10-04
Summary
* discovery and validation of biomarker predicting gastric cancer chemotherapy response
* Analysis for expression level of mRNA using Next generation sequencing in gastric cancer tissue by chemotherapy response
* Analysis for expression level of miRNA using Next generation sequencing in gastric cancer tissue and blood by chemotherapy response
* Validation of mRNA and miRNA using qRT-PCR in multiple independent cohort
* Biological biomarkers-clinical factor combined prediction model of gastric cancer chemotherapy response
Conditions
- Gastric Cancer
- Chemotherapy Effect
- Predictive Cancer Model
Interventions
- DRUG
-
Institutinal standard chemotherapy as first line : XP (xeloda + cisplantin) or Xelox (xeloda+oxaliplitan) +/- Herceptin
Sponsors & Collaborators
-
Kyungpook National University Hospital
lead OTHER
Principal Investigators
-
Su Youn Nam, MD, PhD · Kyungpook National University Medical Center
Eligibility
- Min Age
- 20 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-11-30
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- South Korea
Study Locations
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