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TA-65 and Aging Associated Microvascular Dysfunction

NCT05598359 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2026-05-01

No results posted yet for this study

Summary

The goal of this clinical trial is to test whether activation of telomerase with a dietary supplement (TA-65) improves microvascular function.

Conditions

  • Telomere Shortening
  • Aging
  • Vascular Diseases

Interventions

DIETARY_SUPPLEMENT

TA-65

TA-65 is a purified small molecule extracted from Astragalus root

OTHER

Placebo

Inactive formulation

Sponsors & Collaborators

  • University of Louisville

    collaborator OTHER

  • Penn State University

    collaborator OTHER

  • Medical College of Wisconsin

    lead OTHER

Principal Investigators

  • Andreas Beyer, Ph.D. · Associate Professor

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2027-01-01
Primary Completion
2028-12-31
Completion
2029-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05598359 on ClinicalTrials.gov