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Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium

NCT05594966 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 211

Last updated 2022-10-26

No results posted yet for this study

Summary

Postoperative Cognitive Dysfunction(POCD) is commonly seen in cardiac surgery, which may lead to poor pognosis. Cerebral small vessel disease(CVSD) is refer as the main resource of delirium among elderly people. In the study, CVSD will be diagnosed using multimodal MRI. And we want to select a high correlating COPD biomarker through CyTOF. We also want to investigate a medical model to select the high risk patients who may suffer from POCD after cardiac surgery.

Conditions

  • Postoperative Cognitive Dysfunction
  • Postoperative Delirium
  • Cerebral Small Vessel Diseases
  • Covert Postoperative Stroke

Interventions

DIAGNOSTIC_TEST

multimodal MRI

patients are diagnosed with cerebral small vessel disease preoperatively using multimodal MRI

Sponsors & Collaborators

  • RenJi Hospital

    lead OTHER

Principal Investigators

  • Li Peiying, MD · chief professor of Anesthesiology Departmetn,Renji Hospital

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-11-30
Primary Completion
2025-03-31
Completion
2025-08-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05594966 on ClinicalTrials.gov